Correlation of D-dimer with the Severity of COVID-19 in a Sample of Iraqi Patients in Diyala Governorate

The novel coronavirus disease (COVID-19) is an infectious disease that results in acute respiratory infection or the so-called novel coronavirus (SARS-CoV-2).  At the end of 2019, the Corona virus spread rapidly in almost all countries, which led to the imposition of measures of complete distancing and social distancing. Activation of intravascular coagulation is a common feature of disseminated intravascular coagulation in patients with covid-19. To find out if there is a clot inside the blood vessels (DIC) or if there is a clot inside the lung (pulmonary embolism) of the affected person, this is done by detect level of (D-dimer) in the serum of patients.  This study was conducted to investigate the relationship between D-dimer and disease severity in Iraqi patients infected with (SARS -CoV-2) . Samples were collected from Baladruze General Hospital / Diyala and the confirmed epidemiological  hall (Al-Shaheed  Mortada). The total number of the sample is (100) samples, 50 of which are from people in critical condition in quarantine halls and 50 samples are from healthy people not infected with covid-19 to determine the level of D-dimer. The results of the statistical analysis showed a significant difference in the level of (D-dimer) between infected and non-infected peoples, that the mean D-dimer was 3,0977 ± 2,81828 in the infected peoples, and mean D-dimer among non- infected people, 0.2560 ± 0.13611 with high significant (p < 0.0001). It was concluded that there is a relationship between (D-dimer) and disease severity, and it can be used as an indicator of disease progression, taking into account some cases in which the D-dimer level is elevated.